Indian Journal of Public Health Research & Development
  • Year: 2018
  • Volume: 9
  • Issue: 11

Evaluation of seminal plasma Anti-mullerian hormone levels and their association with sperms’ count and activity in infertile males

1AL-Maaref University College, Iraq

2Ministry of Health, Iraq

Online published on 7 December, 2018.

Abstract

Infertility is a problem that affects approximately 10–15% of couples during their productive ages. Anti-Mullerian hormone (AMH) is produced by Sertoli cells and it regulates male sexual differentiation. Therefore, current study was conducted to evaluate seminal plasma levels of Anti-Mullerian Hormone in fertile and infertile men. Methods: the study was conducted in the General Teaching Hospital in Ramadi city from 1st of February 2018 to 1st of April 2018. Participants were 134 men; 70 patients (who were suffering from infertility) and 64 controls (normal healthy men). The age of participants ranged from 20 to 60 years. Conventional semen analysis was done for all cases and the AMH evaluation was done by ELISA technique. Results: The study showed that there were significant differences in seminal plasma Anti-Mullerian Hormone levels in fertile and non-fertile men with p-alue (<0.05). The study concluded that AMH is a good biomarker for monitoring and treating male infertility and its could be an important cause of men infertility.

Keywords

Seminal plasma, AMH, Sertoli cells, normospermia, azoospermia, men infertility