1PhD Research Scholar & Assistant Professor, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Pallikaranai, Chennai
2Professor & HOD, Department of Biochemistry, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Pallikaranai, Chennai
3Professor, Department of Periodontics, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Pallikaranai, Chennai
4Reader, Department of Periodontics, Tagore Dental College and Hospital, Chennai
5Assistant Professor, Department of Oral Medicine and Radiology, Tamil Nadu Government Dental College & Hospital, Chennai
6Senior Lecturer, Department of Periodontics, Tagore Dental College and Hospital, Chennai
7Assistant Professor, Department of Epidemiology, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education And Research, Pallikaranai, Chennai
8Department of Oral Medicine and Radiology, Tamil Nadu Government Dental College & Hospital, Chennai
*Corresponding Author Dr. V. Aarthinisha, MDs, (PhD), Assistant Professor, Department Of Oral Medicineand Radiology, Tamilnadu Govt Dental College & Hospital, Chennai. 600003. Contact No: +91-9500027640; +91-9443529399
Online published on 9 January, 2019.
To prove that gingival crevicular blood can be used as a novel, minimally-invasive, diagnostic tool to screen undiagnosed diabetic population with gingivitis and periodontitis as compared to invasive phlebotomy and finger puncture blood collection procedures.
To estimate random blood glucose levels from gingival crevicular blood through glucometer. To compare the random blood glucose levels from venous blood by laboratory glucometric methods. To prove that gingival crevicular blood is a minimally invasive diagnostic tool as compared to phlebotomy and finger puncture procedures with good patient compliance.
75 Out-patients with gingivitis and periodontitis who are unaware of their diabetic status undergoing routine intraoral clinical examination will be subjected to periodontal probing after isolating the area to be examined. Blood oozing through the gingival crevice from the anterior maxillary region will be collected by a glucometer for random blood glucose. Samples obtained by phlebotomy technique will be analyzed for random blood glucose through calorimetric methods in the laboratory. Results obtained from both the gingival crevicular blood and venous blood will be compared and statistically analysed. 25 Out-patients who have already been diagnosed as diabetic are included as controls in the study. Correlation between Gingival crevicular blood glucose (GCBG) and Venous blood Glucose (VBG) in total samples were statistically analyzed using SPSS version 11. Highly significant correlation between GCBG & VBG (r=0.993) in total was found. Correlation is highly significant at p<0.01.
Random blood glucose levels measured in GCBG is almost equal to that of VBG. Hence we conclude saying that GCB can be used as a minimally invasive and easy to collect tool for screening diabetes in our routine dental practice as early diagnosis of diabetes helps to prevent its long-term complications, high morbidity and mortality.
Diabetes mellitus, Gingival Crevicular Blood, Minimally invasive, Random Blood Glucose
