1Assist Professor, University of Al-Qadisiyah College of Medicine, Department of internal Medicine
2MB. Ch. B, Al-Dewaniyah Teaching Hospital, Al-Dewaniyah Province Iraq
*Corresponding author: Ghufran Abdulelah Al-Talakani E-mail: ghufranaltalakani@gmail.com Address: Al-Diwaniyah, Iraq, P.O. Box: 88
Online published on 9 January, 2019.
As a bacteria specialized in inhabiting the gastric mucosa, H. pylori is notorious as the chief cause of variable intestinal and extra-intestinal conditions. Yet, the link between H. pylori infection with IBS is still debatable. This has provoked us to execute a case-control study searching into the association between H. pylori status and IBS.
This study is designed to explore the association of H. pylori and the development of IBS, along with revealing if there is any association between this infection and the development IBS.
A descriptive case-control study of 135 individuals was conducted. We select (60) patients from inpatient and outpatient clinic (38 females, 22 males) and were diagnosed as IBS with respect to Rome 4 criteria. Another 75 (42 females, 33 males) seem to be healthy individuals without significant past medical history were assigned as control group. The two groups were subjected to stool antigen for H. pylori and the results were compared between the two clusters.
There was no statistically significant association between HP infection and IBS (p= 0.7). The analysis explored higher prevalence of IBS in younger age group (p= 0.6) with overall female preponderance (p=0.02) and more common in married than single patients (p=0.4, p=0.8; respectively). The most common presentation was diarrhea predominance subtype (p= 0.56).
There is no significant association between H. pylori infection and occurrence of IBS in the general population.
H. Pylori, IBS, Gastric Mucosa
