Indian Journal of Public Health Research & Development
  • Year: 2018
  • Volume: 9
  • Issue: 12

The status of lipid peroxidation system in erysipelas patients on the background of diabetes mellitus

  • Author:
  • Madina Marjokhova1,, Marina Afashagova2, Asiat Marjokhova3, Maryana Nagoeva4, Marina Ivanova5, Marina Nalchikova6, Zarema Tagirova7
  • Total Page Count: 5
  • Page Number: 686 to 690

1Head of the Department Department of infectious diseases, Kabardino-Balkarian State University, Nalchik, Russia

2Associate Professor, Department of infectious diseases, Kabardino-Balkarian State University, Nalchik, Russia

3Assistant Professor, Department of infectious diseases, Kabardino-Balkarian State University, Nalchik, Russia

4Professor, Department of infectious diseases, Kabardino-Balkarian State University, Nalchik, Russia

5Professor, Department of infectious diseases, Kabardino-Balkarian State University, Nalchik, Russia

6Associate Professor Department of infectious diseases, Kabardino-Balkarian State University, Nalchik, Russia

7Assistant Professor, Department of Infectious Diseases, Dagestan State Medical University, Makhachkala, Russia

*Corresponding Author: Madina Marjokhova, Department of infectious diseases, Kabardino-Balkarian state University, Nalchik, Russia (Chernyshevsky st., 173; 360004). Email address: mmarjokhova@yahoo.com

Online published on 9 January, 2019.

Abstract

The erysipelas develops quite rapidly. This infectious disease is characterized by skin inflammation caused by streptococcus. Its progressiveness depends on many factors. The presence of diabetes occupying a leading place in the system of vascular events is one of the most significant factors. In this regard, this article studies the status of a lipid peroxidation system in erysipelas patients on the background of diabetes mellitus.

The experiment was conducted in the Center for Prevention and Control of AIDS and Infectious Diseases (Kabardino-Balkar Republic, Nalchik city). There were two groups participating in the experiment: the first group consisted of 20 erysipelas patients; the second one-of 14 patients, whose erysipelas developed on the background of diabetes mellitus. All patients were taking tablets.

As a result of the experiment, it turned out that lipid peroxidation occurs in biological membranes during the period of erysipelas. This is manifested by an increase in blood MDA level, as well as by a deficit of antioxidant protection and a decrease in the plasma antioxidant (ceruloplasmin).

Recorded changes in considered parameters were more pronounced and returned to normal after treatment on the unfavorable premorbid background-such a serious disease as diabetes mellitus.

Keywords

Ergotism (St. Anthony's fire), diabetes mellitus, antioxidant system, ceruloplasmin level, endointoxication