1Dep. of Biology, College of Science, University of Baghdad, Iraq
2Dep. of Pathology, College of Veterinary Medicine, University of Baghdad, Iraq
*Corresponding author: Mais Emad. Ahmed, Dep. of Biology, College of Science University of Baghdad, Iraq E-mail: mais.e.mahmood@gmail.com
Online published on 2 February, 2019.
Today technology using nanoparticle when treatment pathogentic microorganism and we focused on this here. It was found that the species of streptococcus used in present study were sensitive to erythromycin. In present study focusing bioflm formation by Streptococcus spp was evaluated. Species S. mutans was found that highest amount of bioflm compare with the other species. The aim of report effect (SNPs) on ability of bioflm form different species of streptococcus. The anti-bioflm effect of SNPs was in concentration dependent manner. The highest effect of SNP against bioflm formation was found the concentration 160 μg/ml, while the lowest effect was found the lowest used concentration (80 μg/ml) of SNPs. In vivo study revealed that silver nanopasrticles treatment of Streptococcus pyogenes contaminated injured skin showed good prognosis and good healing process include complete regeneration of the epithelial cells of the epidermis and increase of cellulartiy of the dermal content compared with untreated group. In conclusion, treatment of skin infected with S. pyogenes using silver nanoparticles concentration (160/g/ml) may limited the skin damage, localized the lesion to the incision site and enhance the healing process.
Bioflm, Silver nanoparticle, Streptococcus