1Department of Life Science and Biochemical Engineering, Graduate School, SunMoon University, Korea
2Department of Dental Hygiene, Chodang University, Korea
3Department of Dental Hygiene, Sunmoon University, Korea
4Genome-based BioIT Covergence Institute, Korea
5Department of Pharmaceutical Engineering and Biotechnology, Sunmoon University, Korea
*Corresponding Author: Kun-Ok Lim & Tae-Jin Oh, Professor, Department of Dental Hygiene & Department of Pharmaceutical Engineering and Biotechnology, Sunmoon University, Korea. Email: kolim139@sunmoon.ac.kr, tjoh3782@sunmoon.ac.kr
Online published on 2 February, 2019.
To evaluate antibacterial and antioxidant activities using Pleurotus eryngii extracts.
TPC, TFC, DPPH, and ABTS activities were examined for antioxidant effects. In order to determine the antimicrobial activity, we also studied these extracts using six multi-resistant bacteria through paper disc diffusion.
The content of total polyphenols ranged from 1.67 mg GAE/g extract in acetone extract to 1.31 mg GAE/g extract in EtOH extract. The content of total flavonoid varied from 7.77 mg CE/g extract in EtAC extract to 0.61 mg CE/g extract in EtOH extract. At the result of DPPH activities of all extracts were higher than the ascorbic acid solution. DPPH activity of EtAC extract was the highest value at 81.0%. In addition, the highest ABTS activity was observed in EtOH extract at 88.4%. DPPH activity showed a stronger correlation with TPC and TFC. EtOH extract and acetone extract showed antimicrobial activity against six microorganisms. The EtOH extracts were the most effective against Enterobacter cloacae, and the most significant acetone extracts were the most effective for Escherichia coli.
Based on this study, Pleurotus eryngii can be a good candidate for natural antioxidants and antimicrobials.
Antimicrobial, antioxidant, flavonoid, Pleurotus eryngii, polyphenol
