Indian Journal of Public Health Research & Development
  • Year: 2018
  • Volume: 9
  • Issue: 3

Matricaria chamonbmilla: Bioactive Compounds of Methanolic Fruit Extract Using GC-MS and FTIR Techniques and Determination of its Antimicrobial Properties

1Ministry of Health, Mesan Health office, Mesan city, Iraq

2Department of Biology, College of Science, University of Al-Qadisiyah, Hillah city, Iraq

3Biomedical Science Department, University of Babylon, College of Nursing, Hillah city, Iraq

*Corresponding Author: Imad Hadi Hameed Biomedical Science Department, University of Babylon, College of Nursing, Hillah city, Iraq; Phone: 009647716150716 E-mail: imad_dna@yahoo.com

Online published on 3 April, 2018.

Abstract

Matricaria chamomilla is the most popular source of the herbal product chamomile, although other species are also used as chamomile. The objectives of our study were analysis of the secondary metabolite products. Nineteen bioactive compounds were identified in the methanolic extract of Matricaria chamomilla. The identification of bioactive chemical compounds is based on the peak area, retention time molecular weight and molecular formula. GC-MS analysis of Matricaria chamomilla revealed the existence of the 4-Amino1, 5-pentandioic acid, (R)-lavandulyl acetate, 1, 3-Diazacyclooctane-2-thione, Glucosamine, N-acetyl-Nbenzoyl-, Trans-Traumatic acid, Dodecanoic acid, 3-hydroxy-, Cyclopentanone, 2-cyclopentylidene-, (E) β-Famesene, 1-Naphthalenol, 2-methyl-, Pregn-4-ene, 3, 20-dione, 17, 21-dihydroxy-, bis(O-methyloxime), 9, 12, 15-Octadecatrienoic acid, 2, 3-dihydroxypropyl ester, (Z), Pyrazole[4, 5-b]imidazole, 1-formyl-3-ethyl 6-β-d-ribofuranosyl-, 1, 6-Dioxaspiro[4. 4]non-3-ene, 2-(2, 4-hexadiynylidene)-, 9, 12-Octadecadienoic acid (Z, Z)-, 9-Octadecenamide, (Z)-, 1, 2-Benzenedicarboxylic acid, bis(8-methylnonyl) ester, Carda-4, 20(22) dienolide, 3-[(6-deoxy-3-O-methyl-α-D-allopyra and Campesterol. Maximum zone formation was against Proteus mirabilis 6.01±0.23. Matricaria chamomilla was very highly active against Aspergillus terreus 5.89±0.24.

Keywords

Matricaria chamomilla, Bioactive compounds, Antimicrobial, Methanol, Fruit, GC-MS