1Ministry of Public Health, Maysan Health Department, Mesan Governorate, Iraq
2Department of Biology, College of Science for Women, University of Babylon, Hillah city, Iraq
3Biomedical Science Department, University of Babylon, College of Nursing, Hillah City, Iraq
*Corresponding author: Imad Hadi Hameed Biomedical Science Department, University of Babylon, College of Nursing, Hillah City, Iraq; Phone number: 009647716150716; E-mail: imad_dna@yahoo.com
Online published on 29 May, 2018.
Neisseria gonorrhoeae, also known as gonococci, or gonococcus, is a species of gram-negative coffee bean-shaped diplococci bacteria responsible for the sexually transmitted infection gonorrhea. The objectives of this study were analysis of the secondary metabolite products and evaluation antimicrobial activity. Thirty nine bioactive compounds were identified in the methanolic extract of Neisseria gonorrhea. GC-MS analysis of Neisseria gonorrhea revealed the existence of the Butanoic acid, 2-methyl, Propane, 2-methoxy, Hexanoic acid, 2-methyl, 1-Propaneamine, 3-(methylthio), 7-Methylenebicyclo[3.2.0]hept-3-en-2-one, 1, 2-Benzisothiazol-3-amine tbdms, Propanoic acid, Benzeneethanamine, N-methyl, Phenelzine, Hexanediamide, N, N’-di-benzoyloxy, Benzeneacetic acid, Silane, methylenebis, Ethanamine, N-ethyl-N-[(1-methylethoxy)methyl], 2-Pentanamine, Butanal, 4-hydroxy-3-methyl, o-Allylhydroxylamine, 2-Butanamine, 3-methyl, Hexanal, 2-chloro, Hexanoic acid, 4-octyl ester, Pyrrolidine, 2, 5-dimethyl-1-nitroso, 3-Pentanone, dimethylhydrazone, 1-Pentanol, 2-ethyl, 3-Methyl-1, 4-diazabicyclo[4.3.0]nonan-2, 5-dione, Pyrrolo[1.2-a]pyrazine-1, 4-dione, hexahydro. Nerium olender (Alkaloids) was very highly active 6.800±0.24 mm. The results of anti-fungal activity produced by Neisseria gonorrhea showed that the volatile compounds were highly effective to suppress the growth of Aspergillus flavus (6.800±0.24).
Anti-Microbial, Neisseria gonorrhea, GC-MS, Secondary metabolites
