Detection of Bacterial Causes of Psoriasis and Determination of Some Immunological Aspects in Patients

The present study included 80 swabs and 5ml blood were collected from 80 patients with psoriasis and 80 controls who admitted to margin hospital during the period from November 2016 to May 2017. Culture investigations showed 71 positive bacterial growths instead 79 bacterial positive growth. Staphylococcus aureus was the most common isolate 23 (28.75%) of the total samples. followed by Staphylocoous epidermis14 (17.5%) followed by proteus species 10 (12.5%) followed by Streptococcus pyogenes 8 (10%) followed by Eschericha coli 6 (7.5%) followed by Enterobacter aerogenes 4(5%) followed by Klebsiella pneumonia 3 (3.75%) followed by Pseudomonas aeruginosa 2 (2.5%) followed by Serratia marcescens 1(1.25%) and No growth was shown by 9 (11.25%) of the total isolates. The study deals also with detection of cytokines concentration IL-18 showed increased at in concentration especially in age group (56–60 years) years and reached reach338.333 pg/ml compared to control group. IL22 showed increase in their concentrations in psoriasis patient than in controls particularly at age group (51-55years) years which reached 3028.6667 pg/ml.