Comparison of Tumor Growth in Mice Balb/C Induced Breast Cancer Cells Injected with Corticosteroids and Black Seed Oil Extract

Breast cancer is the main cause of death in malignant disease in women worldwide, including in Indonesia. Treatment of breast cancer has developed the use of herbal seed as a complementary therapy. This study aims to determine the effect of black seed oil on the rate of growth of breast cancer tissue implanted in mice group balb/c subcutaneously. Research carried out by using 24 male experimental animals such as mice balb/c implanted with human breast tumor tissue subcutaneously. Observations were carried out for 30 days by giving black seed oil as much as 0.05 ml/kg/day by subcutaneous injection. The results showed that there was a significant relationship between the provision of black seed oil in reducing the rate of growth of implanted tumors in experimental animals (p <0.001). The results of this study suggest in the use of herbs as an adjunct in the treatment of breast cancer.