Association of HbA1c Levels with Body Mass Index in a Patient Diagnosed with Polycystic Ovary Syndrome

Polycystic ovary syndrome (PCOS) is thought to be the most well-known endocrine issue in ladies of regenerative age manifested with various metabolic disturbances and a wide spectrum of clinical features such as menstrual abnormalities, obesity, and hyperandrogenism. This study was aimed to measure the association between HbA_1c and body mass index (BMI) in PCOS women. This study was performed in AL-Batool hospital for obstetric and gynecological diseases in Ba'quba city/Iraq May 2017 to January 2018. It includes 42 patients with PCOS aging from 20–37 years and 42 healthy control. Fasting venous blood samples were obtained for analysis of fasting blood glucose (FBG), hemoglobin (Hb) and HbA1c. BMI was calculated for all study participants by the present weight in Kg dividing by the square of height in meters. This study involved 42 cases of PCOS (case group) and other 42 participants were free of disease (control group). The mean age among patients of case group was significantly higher than that in control group (26.95 ± 4.77 versus 23.9 ± 2.71, P=0.015). 90.5% of patients in control group had normal BMI level while 42.9% of patients in the case group were class I obese. Mean of BMI among patients of case group was significantly higher than that of the control group (29.84 ± 4.22 versus 22.8 ± 2.02, P=0.001). According to HbA1c level, all patients in control group and 90.5% of patients in the case group were non-diabetic. The mean of HbA1c among patients of case group was significantly higher than that in control group (4.76 ± 0.88 versus 3.9 ± 0.6, P=0.001). In the present study, it was found that there is a significant positive correlation between HbA1c and BMI (r= 0.567, P= 0.001). BMI is positively correlated with HbA1c and associated with glycemic control in PCOS.