Evaluation of the rationality of claims made in drug promotional literature using world health organization guidelines

To evaluate the rationality of claims made in drug promotional literature using World Health Organization guidelines

This was observational, cross sectional and single centre study carried out in Smt. Kashibai Navale medical college and hospital, Pune. Total 315 DPLs (Drug Promotional Literature) were collected from various clinical outpatient departments and were analyzed for WHO criteria for drug promotion. Data was analyzed by using Microsoft office Excel version 2010.

None of DPLs followed WHO guidelines. Most DPLs were from cardiovascular system (n=78, 25%). Generic name, brand name, approved therapeutic uses, dosage form showed 100% fulfillment of criteria. Aspects least fulfilled were adverse drug reaction (37%), precautions and contraindications (32%), references to scientific literature (22%), major interactions (21%). Not a single DPLs mentioned about problematic ingredient. Drug cost, correct dosage regimen and dose adjustment was found in 16%, 12% and 13% respectively. Most of references to scientific literature were from journals (n=91), of that 10 were not retrievable. Name and address of manufacturer was present in only 68% of DPLs. Paper quality was excellent in all DPLs.

None of DPLs fulfilled all criteria laid by WHO. Ethical and rational drug promotion will positively impact drug prescribing behavior.