1College of Pharmacy, University of Babylon, Hillah city, Iraq
2Department of Biology, College of Science, University of Babylon, Hillah city, Iraq
3Biomedical Science Department, University of Babylon, College of Nursing, Hillah city, Iraq
*Corresponding author: Lena Fadhil Hamza, College of Pharmacy, University of Babylon, Hillah city, Iraq; E-mail: lenafadhil94@yahoo.com
Online published on 21 September, 2018.
The aims of our study was analysis of the secondary metabolite products. Twenty five bioactive compounds were identified in the methanolic extract of Bacillus subtilis. GC-MS analysis of Bacillus subtilis revealed the existence of the Phenyl-β-D-glucoside, Carbamic acid, phenyl ester, Phenol, 1, 5-Pentanediamine, 9-Octadecenoic acid (Z)-, phenylmethyl ester, 2-Pyrrolidinone, 2H-Pyran, tetrahydro2-(12-pentadecynyloxy), Benzeneethanamine, 2, 6-Dimethyl-8-oxoocta-2, 6-dienoic acid, methyl est, 2-Piperidinone, 3-(Prop-2-enoyloxy) dodecane, DI-[1, 3, 2]-oxazino[6, 5-f: 5’, 6’-H]quinoxaline, 3-[N-[2Diethylaminoethyl]-1-cyclopentenylamino], Pterin-6-carboxylic acid, 3-Trifluoroacet oxytetradecane, 3-Methyl-1, 4-diazabicyclo[4.3.0]nonan-2, 5-dione, Pyrrolo[1, 2-a]pyrazine-1, 4-dione, hexahydro, Cyclopentane, 1, 2-dipropyl, 2-Chloropropionic acid, decyl ester, n-Hexadecanoic acid, 3-Chloropropionic acid, heptadecyl ester, 12-Methyl-oxa-cyclododecan-2-one, 2H-benzocyclohepten-2-one, decahydro4a-methyl, Octadecanoic acid. Bacillus subtilis produce many important secondary metabolites with high biological activities. Based on the significance of employing bioactive compounds in pharmacy to produce drugs for the treatment of many diseases, the purification of compounds produced by Bacillus subtilis can be useful.
Bacillus subtilis, GC-MS, Secondary metabolites
