1Assitant professor, Department of Pathology, NRI Medical College, Chinakakni, Guntur-522503, Andhra Pradesh
2Professor, Department of Pathology, NRI Medical College, Chinakakni, Guntur-522503, Andhra Pradesh
3Professor and HOD, Department of Pathology, NRI Medical College, Chinakakni, Guntur-522503, Andhra Pradesh
4Professsor, Department of Pathology, NRI Medical College, Chinakakni, Guntur-522503, Andhra Pradesh
5Associate Professor, Department of Pathology, NRI Medical College, Chinakakni, Guntur-522503, Andhra Pradesh
6Assistant Professor, Department of Pathology, NRI Medical College, Chinakakni, Guntur-522503, Andhra Pradesh
*Corresponding author E-mail: dratc_mathi@yahoo.in
Online published on 10 October, 2016.
Histopathology is the gold standard in the diagnosis and management of prostatic adeno carcinomas. The objectives of this study are
The study was done on 370 prostatic specimens over a period of 4 years from June 2011 to June 2015 which included both transurethral resection of prostate chips and needle core biopsies received in the department of Pathology, NRI Medical College, Chinakakani. The study included only prostatic adenocarcinomas which constituted to 75 cases out of 370 cases, with the incidence of 20.3%
Prostatic adeno carcinomas were common in the age group of 70–79 years with the three common symptoms of dysuria, incomplete voiding and frequency. The most common primary microscopic pattern was Gleason's pattern 3, followed by pattern 4. The most common Gleason's score was 7 (43%) which showed PSA values in the range of 21–50 ng/ml. The p value for serum PSA levels and Gleason score was 0.00001.
The present study showed a strong correlation between Gleason's score and PSA values. It is concluded that as the Gleason's score increases the serum PSA values also increases
Adenocarcinoma of prostate; Gleason`s score; Prostate specific antigen; Trans urethral resection of prostate
