1Associate Professor, Department of Pathology, ESIC Medical College & PGIMSR, KK Nagar, Chennai, 600078
2Assistant Professor, Department of Pathology, ESIC Medical College & PGIMSR, KK Nagar, Chennai, 600078
3Head of the department, Department of Pathology, ESIC Medical College & PGIMSR, KK Nagar, Chennai, 600078
*Corresponding Author: E-mail: drkms75@gmail.com
Online published on 10 October, 2016.
1. To demonstrate the patterns in different premalignant lesions of prostate. 2. Correlating AgNOR counts with various grades of PIN.
This study was conducted in 83 cases of different prostatic biopsy specimens from 2013–2015. All biopsy samples were routinely processed and stained with both haematoxylin and eosin and with AgNOR stain.
The mean AgNOR count and score of high grade prostatic intraepithelial neoplasia was significantly high when compared to low grade intraepithelial lesion. High grade prostatic intraepithelial lesions associated with nodular hyperplasia or with carcinoma was the same.
AgNOR is a simple, cost effective and easy stain to evaluate the proliferative activity of the cell. It can be used as an additional test which will be of immense value regarding the progression of preneoplastic lesions in prostate.
AgNOR, low grade PIN, high grade PIN
