1Associate Professor, Vinayaka Missions Kiruananda Variyar Medical College, Salem
2Assistant Professor, Vinayaka Missions Kiruananda Variyar Medical College, Salem
3Professor, Dept. of Pathology, DM Waynad Institute of Medical Sciences, Waynad
4Professor, Dept. of Community Medicine, Adichunchangiri Institute of Medical Sciences, Mandya
*Corresponding Author: Email: medicoprakash@gmail.com
Online published on 10 October, 2016.
Assigning a score to cytology/FNA of thyroid lesions can provide important information regarding their neoplastic or non-neoplastic nature. The present study was undertaken to score thyroid lesions on aspirates based on various characteristics and correlating with standard cytological classification. Histopathology was done and the two cytological classification systems (Cytological scoring and Standard method) were compared.
196 cases of thyroid lesions with preoperative cytologic diagnosis were assigned cytological score/classified. Histopathology diagnosis was compared and statistical analysis was performed; correlation between cytologic score and histopathology was established using Spearman correlation coefficient. Regression analysis was done to assess the significance of each cytological score.
Multivariate analysis of cytologic features revealed that the amount of colloid, nuclear features and background pattern are the most influential features. There was high degree of correlation between the scoring methods on cytology with histopathology compared to standard cyto classification with histopathology. There was a significant association (p<0.001) between the scores assigned to cytologic and histopathologic specimens.
Cytological scoring method can be used to assess the lesions of the thyroid as a significant relationship exists between both the classification systems and histopathology.
FNAC, Cytological scoring, Statistical analysis
