1Associate Professor, Dept. of Pathology, Lokmanya Tilak Memorial Medical College, Sion, Mumbai
2Assistant Professor, Dept. of Pathology, Lokmanya Tilak Memorial Medical College, Sion, Mumbai
*Corresponding Author: Email: drsvgoyal@gmail.com
Online published on 10 October, 2016.
Meningiomas are slow-growing and benign tumor of the meninges, which line the skull and enclose the brain.
We have studied 324 cases of meningeal lesions (clinically diagnosed and histologically proved) in Department of Pathology of a tertiary care hospital. We evaluated its frequency, age and sex distribution and documented as per the WHO histological grade of meningioma.
The commonest age group affected was 41–60 years. Female predominance was seen. Headache being most common symptom with commonest site was intracranial (88.2%). The meningeal lesions consisted of meningioma (96.6%) and nonmeningioma lesions (3.4%). The commonest histopathological type of mengioma was transitional (24.2%) followed by meningotheliomatous (22.8%). The 85.6% of the meningioma was WHO Grade I tumor. For WHO Grade II meningiomas, mitotic figures and high cellularity was helpful to diagnose the tumors. The non-meningioma lesions included hemangiopericytoma, solitary fibrous tumor, malignant melanoma and metastasis by carcinoma breast, lung and thyroid.
From our study, we can conclude that benign meningiomas WHO grade I are most common. Intracranial location is the most common for meningioma. Middle-aged group of 41–60 years was predominently affected and it is uncommon in children.
Meningeal neoplasms, Meningioma, WHO grade
