An autopsy case report on OEIS Complex

OEIS complex is a rare congenital anomaly characterised by omphalocele, exstrophy of bladder, imperforate anus and spinal defects. It is a defect that affects the midline of the lower inferior body. This condition is mostly fatal and almost incompatible with life. A diabetic multiparous woman with history of previous 2 spontaneous abortions presented with 3rd pregnancy, spontaneously delivered a dead fetus of 17weeks gestational age. Here we present an autopsy case report of a 17 weeks fetus with features of OEIS complex which had the above mentioned features along with left club foot, absence of spleen, pancreas & both internal and external genitalia. Microscopic examination of the placenta showed villi with fibrin clot deposition and calcification suggesting that feto-maternal insufficiency of placenta was the cause of death.