In a greenhouse study, significant responses of wheat to N and Cu were observed upto 60 ppm N and 5 ppm Cu. Increasing supply of N and Cu significantly increased the concentration and uptake of respective nutrients by the crop. Nitrogen application showed antagonistic effect on Cu content and Vice versa. An increase in Cu uptake was noted upto 60 ppm applied N whereas N uptake increased with 2.5 ppm Cu application.