Indian Journal of Pharmacy and Pharmacology
  • Year: 2015
  • Volume: 2
  • Issue: 4

Evaluation of Antioxidant and Anticholinesterase Potential of Bark Extracts of Alstonia Scholaris

1Assistant Professor, Department of Pharmacology, JSS College of Pharmacy, Udhagamandalam

2Lecturer, Department of Pharmacology, JSS College of Pharmacy, Udhagamandalam

3M Pharma, Department of Pharmacology, JSS College of Pharmacy, Udhagamandalam

*Corresponding Author: Email: praveentk@sscpooty.org

Online published on 12 August, 2016.

Abstract

The present study was carried out to investigate the in-vitro antioxidant and anticholinesterase potential of the bark extracts of Alstonia scholaris. The ethylacetate and methanolic extracts of the bark was prepared by successive soxhlet extraction method. The in-vitro antioxidant and anticholinesterase activity were assessed by DPPH assay and rat brain cholinesterase assay. The results of the study show that the ethyl acetate and methanolic extracts possess significant antioxidant and cholinesterase inhibitory activity.

Keywords

Alstonia scholaris, Alzheimer's, antioxidant, anticholinesterase, ethyl acetate extract