Indian Journal of Pharmacy and Pharmacology
  • Year: 2016
  • Volume: 3
  • Issue: 1

Phytochemical and In-Vitro Evaluation of Antioxidant Activity of Sesamum Indicum Leaves

  • Author:
  • K Vani1, M Malathi Priyanka1, P Durga Srinivas1, U Naveen Kumar1, Y Kalyani1, SK Aminabee2,, A Lakshmana Rao3
  • Total Page Count: 6
  • Page Number: 7 to 12

1Student, Department of Pharmacology, V. V. Institute of Pharmaceutical Sciences, Gudlavalleru, Andhra Pradesh, India

2Associate Professor, Department of Pharmacology, V. V. Institute of Pharmaceutical Sciences, Gudlavalleru, Andhra Pradesh, India

3Professor and Principal, Department of Pharmacology, V. V. Institute of Pharmaceutical Sciences, Gudlavalleru, Andhra Pradesh, India

*Corresponding Author: E-mail: aminaammi786@gmail.com

Online published on 12 August, 2016.

Abstract

The aim of the present study was to evaluate preliminary phytochemicals and in-vitro evaluation of antioxidant activity of Sesamum indicum leaves.

Antioxidant activity was evaluated by using in-vitro antioxidant assay models like hydrogen peroxide scavenging activity, reducing power assay and phosphomolybdenum method. All the antioxidant activities were compared with standard antioxidant such as ascorbic acid.

The ethanolic extract of Sesamum indicum leaves was found to contain flavonoids. Additionally, the capacity to scavenge hydrogen peroxide, the reducing power (capacity to reduce Fe3+ to Fe2+) and formation of phosphomolybdenum complex were evaluated. From this study it was concluded that the extract exhibited a concentration dependent scavenging activity.

Keywords

Sesamum indicum, Flavonoids, Hydrogen peroxide scavenging, Reducing power, Phosphomolybdenum complex