Evaluation of the locomotor and skeletal muscle relaxant activities of ethanolic extracts of Acacia Nilotica Linn. BARK. (Mimosaceae)

Acacia nilotica Linn. Subsp. indica (Family-Mimosaceae) bark has many activities like anti-plasmodial, molluscidal, anti-fungal, anti-microbial activity. The plant has no CNS depressant action found yet, but having such good number of beneficial action to human being has drawn our interest to study the same. The aim of the present study is to investigate the CNS depressant activity of ethanolic extracts A.nilotica bark on mice. The CNS depressant activity was determined by muscle relaxant property, reduction in spontaneous motility. The investigations had brought out that ethanolic extract of Acacia nilotica bark has significant CNS depressant property.