1Senior Resident, Dept. of Medicine, King George Medical University, Lucknow
2Associate Professor, Dept. of Medicine, King George Medical University, Lucknow
3Assistant Professor, Dept. of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi
4Professor, Dept. of Medicine, King George Medical University, Lucknow
5Professor & HOD, Dept. of Medicine, King George Medical University, Lucknow
*Corresponding Author: Email: dranjudinkar@gmail.com
Online published on 23 June, 2017.
Steven-Johnson Syndrome (SJS) is a severe, episodic, acute mucocutaneous reaction characterized by blisters and epidermal detachment resulting from epidermal necrosis in the absence of substantial dermal inflammation. We report a case of 64-year old male farmer who developed Stevens-Johnson syndrome following the ingestion of Sodium Valproate monotherapy prescribed for seizure disorder. He was treated with intravenous corticosteroids, antihistamine, antibiotics and supportive therapy. We are presenting this case to highlight the serious adverse effect of commonly prescribed antiepileptic drug, sodium valproate as a monotherapy.
Sodium Valproate, Steven-Johnson Syndrome, Seizure Disorder, Mucocutaneous reaction, Corticosteroid
