Indian Journal of Pharmacy and Pharmacology
  • Year: 2017
  • Volume: 4
  • Issue: 3

Synthesis and antimicrobial screening of some novel quinazolinones and its derivatives

  • Author:
  • B. Satya Sree1,, A. Lakshmana Rao2, P. Swathanthra Babu3, K. Surya Kiran3, K. Vandana3
  • Total Page Count: 4
  • Page Number: 130 to 133

1Associate Professor, Dept. of Pharmaceutical Chemistry, VV Institute of Pharmaceutical Sciences, Gudlavalleru

2Principal & Professor, Dept. of Pharmaceutical Chemistry, VV Institute of Pharmaceutical Sciences, Gudlavalleru

3Student, Dept. of Pharmaceutical Chemistry, VV Institute of Pharmaceutical Sciences, Gudlavalleru

*Corresponding Author: Email: satyasree.bandaru@gmail.com

Online published on 3 April, 2018.

Abstract

Various novel quinazolinones and quinazolidine dione derivatives were prepared by using anthranilic acid. Anthranilic acid was synthesized by treating phthalimide with sodium hypobromide solution. The synthesized anthranilic acid was treated with urea, thiourea, acetamide and benzamide to give corresponding titled compounds in good yields. The synthesized compounds were characterized by physical properties and spectral studies (IR, 1H-NMR) and tested for antimicrobial activity.

Keywords

Anthranilic acid, Urea, Thiourea, Benzamide, Quinqzolinones and Quinazolidine diones