Retrospective analysis on adverse drug reactions prevalence in the female population of Tertiary Care Hospital

Adverse drug reactions seems to be a major problem in women than men.

This study as planned to assess the incidence rate, clinical manifestations, and causative agents for adverse drug reactions (ADRs) in female patients.

This study was a retrospective study in which analysis of the clinical variables related to all suspected cases of ADRs reported in female patients of the tertiary centre hospital.

Out of 206 patients reported with ADR in between period of 2012 to 2015, 110 (53.4%) were female whereas only 46.6% were male patients. Although Mean age of female patients affected from ADRs was 31.53 years and most of ADRs were reported in the age group of 20–39 years (41.8%). Department of dermatology has reported maximum number of ADRs in females (51, 46.36%), followed by medicine (21, 23.6%) and Surgery (19, 17.02%). Amongst 85 ADRs cases reported due to antimicrobial, betalactams (31, 36.5%) and quinolones (17, 20%) were the mostly responsible, followed by aminoglycosides (11, 12.9%). Skin was affected more frequently (69.6%), followed by gastrointestinal (14.9%).

Adverse drug reactions in female seems to be a significant problem and we need to evaluates the physiological and other cofactors to understand the high occurrence of adverse drug reaction in females.