Transferable drug resistance, bacteriocinogeny and serum resistance in Salmonella Gallinarum avian strains

Field strains of Salmonella enlerica subspecies enlerica biovar gallinarum (Salmonella Oallinarum -SG) were tested for R-factor mediated conjugative transfer of drug resistance, bacteriocinogeny and serum resistance to a recipient E. coli (K₁₂ F-lac Nal) strain. Out of 15 strains of SG, 6 (40%) transferred enbloc resistance against tetracycline, gentamicin as well as sulfamethoxazole (TGS) and 5 (33.3%) transferred enbloc resistance against GS while four (26.6%) failed to transfer drug resistance. Ten strains were investigated for transfer of bacteriocinogeny. 7 (70%) could transfer bacteriocinogeny to the recipient strain, while none out of eight strains could transfer resistance against bacteriolytic activity of guinea pig and chicken serum. The possible implications of these factors in the treatment and pathogenesis of S. Gallinarum infection has been discussed.