Department of Animal Breeding and Genetics, College of Veterinary Sciences, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana - 141 004, (Punjab).
*Corresponding author: E-mail: samitasaini123@yahoo.com
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Immunocompetence of White Leghorn and Rhode Island Red strains was evaluated on three White Leghorn and two Rhode Island Red strains as humoral response to T dependent antigen SRBC and in vivo cell mediated immune response to mitogen Phytohaemagglutinin (PHA-P). Immune response to sheep red blood cells measured as Total, MER and MES titre at 0, 4, 9, 14 and 21 days post primary inoculation had peak titre value at 9 days PPI for total and MER and 4 days PPI for MES titre. Haemagglutination titre gives indication of total antibodies while MER and MES titre represented level of Immunoglobin G (Ig G) and Immunoglobulin M (Ig M) respectively. MES titre had higher value than MER titre at all stages. The White Leghorn selected strains had higher total, MER and MES titre before inoculation with sheep red cells than RIR strains while RIR strains had higher total, MER and MES titre at all stages PPI than White Leghorn strains. Thus Rhode Island Red strains had lower level of antibodies against SRBC naturally but when exposed to SRBC antigen they gave higher immune responsiveness. Of White Leghorn selected strains PL2 had better immune responsiveness compared to PL1 and control except for MES level, which was higher in control than PL2. The in vivo cell mediated immune response as measured by T-lymphocyte proliferation response to mitogen Phytohaemagglutinin was highest in White Leghorn control line.
Immunocompetence, White Leghorn, Rhode Island Red, sheep red blood cells, phytohaemagglutinin
