1Division ofAvian Physiology and Reproduction, ICAR-Central Avian Research Institute, Izatnagar, Bareilly-243122 (UP), India
2Division of Pathology, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly-243122 (UP), India
3Division of Post-Harvest Technology, ICAR-Central Avian Research Institute, Izatnagar, Bareilly-243122 (UP), India
*Corresponding Author Email: ashim.biswas@icar.gov.in
The aim of this study was to evaluate the effect of non-conventional dietary fibres (NCDF) and vitamin E on body weight gain, obesity, serum lipid profiles, antioxidant enzyme activity, hepatic and renal functions, glucose metabolism and protein turnover through a systematic and well controlled mice model study. A total thirty six adult male Swiss albino mice were housed in 3 groups. They were provided three different samples viz., (1) basal diet (BD), (2) control finger chip (no added fiber/vita, CFC) and, (3) functional finger chips (FFC) supplemented with NCDF and vitamin E for 90 days. All parameters were determined at each month while adipose tissue accumulation was determined at the end of the experiment. Results indicated that feeding of CFC and FFC reduced body weight gain, but adipose tissue deposition was little affected. Lowest serum total cholesterol (TC) was exhibited by BD fed group. The activity of hepatic and renal enzymes as well as antioxidant enzymes indicated protective effects against indices of chronic diseases by the functional compounds. Greater serum total protein and better control on glucose level were exhibited by FFC group and all vital organs were normal. It was concluded that isolated non-conventional fiber and vitamin E supplementation ameliorates weight gain and have protective effect on oxidative stress related chronic diseases in mice.
Dietary fibers, Obesity, Functional meat, Glucose, Mice