Identification of an antibacterial potential marine Streptomyces sps from Sargassum fluitans

The discovery of new broad antibiotics is an urgent need to combatfrequently prompting diseases for social welfare. The marine environment posses most diverse environment from which novel secondary metabolites can be derived. The various number of bioactive compound has been identified from marine samples. To address this issue, there is chance for identifying bioactive compounds from marine actinomycetes. The aim of study was to isolate and identify secondary metabolites producing actinomycetes from marine algae (Sargassumfluitans.). The isolate SW A4 were partially characterised by morphological and biochemical methods. Their antibacterial activity werefurther analysed by preliminary and Disc diffusion assays. Interestingly, the SW A4 isolate showed excellent inhibition activity aganist certain disease causing human pathogenic bacteria. Here the methanolic extract showed efficient activity of 12,17,13,12 mm zoneaganist S.typhi, K.pneumonia, E.coli, B.cereus respectively.