Invertis Journal of Renewable Energy
  • Year: 2020
  • Volume: 10
  • Issue: 4

Efficient One-Pot, Three-Component Reaction of Isocyanides, Acetylene dicarboxylate, and Quinolone: Synthesis of Novel Spiro heterocycles

1Department of Chemistry, Invertis University Bareilly, Uttar Pradesh, India

*Corresponding author e-mail id: kuldeep.c@invertis.org

Abstract

Isocyanides-based multicomponent strategy for the construction of highly functionalized quinolones derivatives has been developed under mild conditions, in which few derivatives obtained in moderate to good yield. This is a mechanistic study of the carbonyl group of quinolone. A simple and convenient isocyanide-based multicomponent reaction for the construction of highly functionalized quinolones derivatives has been developed under mild conditions.

Keywords

Carbonyl group, Isocyanide, Medicinal chemistry, Multicomponent reaction, Quinolones