Research Scholar, Department of Biotechnology, Acharya Nagarjuna University, Guntur-522510
Online published on 20 July, 2015.
Over the centuries, traditional cultures around the world have learned how to use phytomedicines to fight illness and maintain health. Medicinal plants contain a wide range of metabolites that can be used to treat chronic as well as infectious diseases. In spite of tremendous development in the field of synthetic drugs and antibiotics during the 20th century, plants still continue to be a major source of drugs in modern as well as traditional systems of medicine throughout the world. The present study is focused on the extraction of secondary metabolites from the medicinal plant Decalepis hamiltonii (Wight and Arn.) (family: Asclepiadaceae), is an endemic and endangered to the southern peninsula. The study was designed to screening the phytocompounds qualitatively, quantitatively and evaluates the anthemintic and anti microbial activity of methanolic root extract of the selected plant against the Indian Earthworm Pheretima posthuma and pathogenic microorganisms respectively. Different concentrations of methanolic extract were tested and results were expressed in terms of time for paralysis and time for death of worms for antihelmenthic and zone of inhibition for antimicrobial activity. The methanolic roots extract shows the better results compare to the control.