Effect Of Glucose on Cell Capacitance: Simulation in MEMS

It is to be noted that membrane capacitance changes with diabetes, which is one of the fatal diseases in the world nowadays. Long term diabetes affects the immunity resulting to various disorders of the body. Fibrosis in the pancreas as well as myocardium is one of the major problems related with long term diabetes. Once fibrosis starts the capacitance of the cell linked to fibrosis will vary at different stages. The variation of the capacitance has been linked with the capacitance relaxation phenomena through simulation in MEMS. It is now well established that MEMS is diagnostic instrumentation for assessment of the status of diseases. The authors tried to measure the concentration of glucose with the help of Bio MEMS for establishing the fact that the capacitance of the living cell changes with the change in glucose in the body. The cellular transduction linked to capacitance relaxation phenomena has been focused through simulation in MEMS. The cellular transduction is also linked with growth of fibrosis in diabetic mellitus.