1Department of Internal Medicine, Kerala Institute of Medical Sciences, Thiruvananthapuram, Kerala-695029, India
*Address for correspondence: P. Arjun, Department of Respiratory Medicine, Kerala Institute of Medical Sciences, P.B. No.1, Anayara, P.O, Thiruvananthapuram, Kerala-695029, India, Email: dr.p.arjun@gmail.com
**Email: drhsj83@rediffmail.com
***Email: amnavita@gmail.com
Online published on 5 August, 2017.
The metabolic syndrome (MS) and obstructive sleep apnoea (OSA)are associated with an increased risk for cardiovascular disease. There are a number of studiesinvestigating the relationship of OSA and MS, but the literature from India is scarce. This studyaimed to investigate the relationship of OSA and MS in Indian subjects. The aim of this studyis (1) the prevalence of MS in patients with OSA, (2) whether the presence of MS correlates withthe severity of OSA, and (3) the association of OSA and the components of MS.
A cross-sectional, prospective study in which 110 adult patients undergoingovernight polysomnography was conductedand analysed for the presence of MS. OSA wasdefined as apnoea-hypopnoea index (AHI) =5 events/h. MS was diagnosed as per thedefinition by National Cholesterol Education Program, Adult Treatment Panel III criteria. Subjects were assessed for presence of OSA, MS, and correlation of severity of OSA with MSand association of each of the component of MS with OSA.
Out of the 110 subjects, 81 were found to have OSA; the remaining 29 subjectswere taken as controls. Out of 81 subjects with OSA, 61 (75.30%) had MS and 9 (31.03%)out of 29 controls had MS.
Subjects with OSA (1) had significantly higher prevalence of MS as compared to controls, (2) had higher systolic and diastolic blood pressures, (3) had hyperglycaemia, (4) had lower HDL cholesterol level, and (5) had differences in triglyceridesand waist circumference that was not statistically significant.
Metabolic syndrome, Obstructive sleep apnoea (OSA)
