Vardhman Mahavir Medical College & Safdarjung Hospital, New Delhi
*Address for correspondence: Dr J C Suri Consultant, Professor & Head Department of Pulmonary, Critical Care & Sleep Medicine, Vardhman Mahavir Medical College & Safdarjung Hospital, New Delhi Email: docjcsuri@gmail.com
Online published on 10 May, 2018.
Sleep disordered breathing (SDB) is being recognized as a risk factor for stroke. OSA is easily modifiable; the diagnosis is simple, and the treatment straight-forward. These characteristics make OSA an ideal target for interventions aimed to reduce cerebrovascular disease burden. However, data from India is lacking.
Fifty subjects with a history of recent onset stroke, and hundred matched controls were recruited. A comprehensive history and other relevant features were recorded. After the acute phase of the stroke was over, the patients underwent an overnight polysomnography (PSG). The sleep architecture was also analyzed.
SDB was seen in 78% stroke patients but in only 28% of controls (OR 9.1169 (95% CI 4.1009 to 20.2684) P < 0.0001). Mixed apnea was seen in 53.85% of the cases and was the predominant type of sleep apnea observed. The prevalence of SDB was high in stroke patients with obesity and congestive cardiac failure. We found a reduction in total sleep time, sleep efficiency and REM sleep in stroke patients and an increased stage 2 sleep. Also, stroke topography affected sleep architecture with patients with multiple sites involved having decreased REM sleep.
Stroke, Cerebro-vascular accident (CVA), Sleep disordered breathing (SDB), polysomnography (PSG), sleep architecture
