Indian Journal of Sleep Medicine
  • Year: 2016
  • Volume: 11
  • Issue: 4

Association of Hypothyroidism in Obstructive Sleep Apnea Syndrome

Department of Pulmonary Medicine, 2nd floor, OPD bldg, TNMC & BYL Nair Hospital, AL Nair Road, Mumbai Central, Mumbai-400008

*Address for correspondence: Dr. Jyotsna M. Joshi Department of Pulmonary Medicine, 2nd floor, OPD bldg, TNMC & BYL Nair Hospital, AL Nair Road, Mumbai Central, Mumbai-400008 Email - drjoshijm@gmail.com, Ph no-02223003095

Online published on 30 June, 2018.

Abstract

Hypothyroidism and obstructive sleep apnea syndrome (OSAS) are common comorbid conditions with overlapping clinical presentation. We decided to study the association of hypothyroidism in our OSAS patients.

This observational study included 108 patients with clinical features suggesting OSAS. The clinical details were noted; Polysomnography (PSG) and thyroid function tests (TFT) were done. Qualitative and quantitative data was analyzed with appropriate tests.

Seventy-two (66.7%) men and 36 (33.3%) women were included. PSG confirmed OSAS in 78 (72.2%). The severity of OSAS was mild, moderate, severe in 30 (38%), 28 (36%), 20 (26%) respectively. Thirteen (12%) had hypothyroidism; subclinical in 2 (15%) and clinical in 11 (85%). Only 2 (15%) were on optimal medical treatment. Hypothyroidism was seen in 11(14%) of OSAS, against in 2(7%) of the non-OSAS group. OSAS was found in 11(85%) of hypothyroid, against in 67 (71%) of the Euthyroid group. A statistically significant association between OSAS and hypothyroidism treatment was observed.

The prevalence of hypothyroidism was higher in OSAS; though statistically insignificant. Association between OSAS and hypothyroidism treatment was statistically significant.

Keywords

Apnea-hypopnea index (AHI), Polysomnography, Thyroid function tests (TFT), OSAS, Hypothyroid treatment