Indian Journal of Sleep Medicine
  • Year: 2010
  • Volume: 5
  • Issue: 4

Revisiting Kleine-Levin Syndrome – a case report and review

  • Author:
  • CHua Ai-Ping, Prakash Kotagal, Jyoti Krishna, Chua Ai Ping
  • Total Page Count: 5
  • Page Number: 111 to 115

Sleep Fellow Sleep Disorder Center, Cleveland Clinic Foundation

Address for correspondence: Dr Chua Ai Ping, Sleep Fellow, Division of Respiratory & Critical Care Medicine, Dept of Medicine, National University Heathcare, System, IE Kent Ridge Road, NUHS Tower, Block Level 10, W10229, Singapore 119228

Abstract

A 15 year-old girl who was previously well presented with severe recurrent episodic hypersomnia associated with abnormal behavior and hyperphagia after recovery from a mild upper respiratory tract infection (URTI). Physical examination was unremarkable with normal blood tests, brain imaging and electroencephalogram (EEG). A multiple sleep latency test (MSLT) during a typical episode showed moderate hypersomnolence in contrast to a normal MSLT performed an the interval between episodes. Clinical features were consistent with Kleine-Levin syndrome (KLS). She was started on carbamazepine treatment after failing a trial of methylphenidate and is currently being followed up for her symptoms.

Keywords

Hypersomnia, Episodic, Recurrent, Multiple sleep latency test, Polysomnogram, Carbamazepine, Hyperphagia, Kleine-Levin Syndrome