Indian Journal of Sleep Medicine
  • Year: 2013
  • Volume: 8
  • Issue: 4

Weight gain in patients with Obstructive Sleep Apnea (OSA) on Positive Airway Pressure (PAP) therapy – Myth or Reality?

Nithra Institute of Sleep Sciences, Chennai, India

*Address for correspondence: Nagarajan Ramakrishnan AB (Int Med), AB (Crit Care), AB (Sleep Med), MMM, FACP, FCCP, FCCM, FISDA, FICCM Senior Consultant & Director, Nithra Institute of Sleep Sciences, Door # 29 (Plot # 1997), J Block, 13th Main Road Annanagar, Chennai 600 040. Ph: +91 44 4350 2252; Email: ram@nithra.com

Online published on 28 October, 2014.

Abstract

Obesity is recognized as one of the predominant risk factor for Obstructive Sleep Apnea (OSA). Even moderate reduction in weight and body mass index (BMI) could reduce the severity of OSA and is recommended as part of comprehensive therapeutic approach in patients who are prescribed Positive Airway Pressure (PAP) therapy. However, this remains a challenge for most patients and some may even report weight gain. In this article, we report a case history highlighting weight gain while on PAP therapy and review the literature on this phenomenon.

Keywords

Obstructive Sleep apnea, Continuous positive airway pressure, Leptin, Body mass index