Anti-stress activity of Tinospora cordifolia in goats maintained under different managemental conditions

The study was conducted to evaluate the anti-stress potential of Tinospora Cordifolia (Guduchi/Amruta) on solar radiation-induced heat stress in goats maintained under different management systems. The experiment was conducted in 12 native, non-descript goats with average body weight of 32.0±0.5 kg. Plant powder (@500 mg/Kg body weight) was orally administered daily for 30 days. The anti-stress activity of T. cordifolia was investigated by measuring changes in lipid peroxidation, glutathione level and superoxide dismutase activity in erythrocytes of goats. In untreated goats, there was a significant increase in the lipid peroxidation level and a significant reduction in the reduced glutathione and superoxide dismutase activity. In T. cordifolia supplemented animals the heat stress was significantly (P<0.05) reduced, which was indicated by change in the anti-oxidant profile. Oral administration of T. cordifolia plant powder modulated the lipid peroxidation, reduced glutathione and superoxide dismutase level of near normal in heat stressed goats.