Efficacy of clomiphene citrate in augmenting fertility of anoestrous goats

A study was designed to assess the efficiency of clomiphene citrate in augmenting fertility in anoestrous goats. Fifty-two pluriparous goats (2-6 yr old) with the history of anoestrus since last kidding were taken for the study. Animals were divided into two groups. Animals of Gr-I (n=26) were treated with TANUVAS mineral mixture type 2 (10 g/day) for 20 days orally. Animals of Gr-II (n=26) were treated with TANUVAS mineral mixture type 2 (10 g/day) for 20 days followed by clomiphene citrate 150 mg (Ovulanta-Kit, Vet Mankind, India) orally for five days. Follicular activity was observed by ultrasonography after supplementation of mineral mixture in both the groups until pre-ovulatory follicle size of > 5 mm, followed by administration of buserelin acetate (40μg, intramuscular). In Gr-I, 16 (61.5%) animals showed pre-ovulatory follicles in 52 days interval whereas in Gr-II, 24 (92.3%) animals showed in five days post treatment with clomiphene citrate. In both the groups, 50.0% of the animals were allowed for natural mating and the remaining were artificially inseminated (AI) with frozen semen. In Gr-I, 37.5% (3/8) and 62.5% (5/8) animals conceived by natural mating and AI, respectively; whereas, the corresponding values in Gr-II were 75.0% (9/12) and 100.00% (12/12). The results showed the potent efficiency of clomiphene citrate in the treatment of anoestrus in goats.