Indian Journal of Small Ruminants (The)
SCOPUS
  • Year: 2023
  • Volume: 29
  • Issue: 1

Data mining uncovers non-coding RNAs from RNA sequences of skeletal muscles in Indian sheep

  • Author:
  • Pooja Chhabra1, Brij Mohan Goel1, Sonika Ahlawat, Anil Kumar Mishra, Reena Arora*
  • Total Page Count: 4
  • Page Number: 32 to 35

1Baba Mastnath University, Asthal Bohar, Rohtak-124 021, Haryana

ICAR-National Bureau of Animal Genetic Resources, Karnal-132 001, Haryana

*E-mail address: reena.arora@icar.gov.in

Online published on 15 February, 2023.

Abstract

A study was attempted to identify the different types of non-coding RNA from skeletal muscles of Indian sheep. RNA sequencing data of muscle samples of 4 Bandur and 4 non-descript sheep were analyzed to identify the diverse non-coding RNA molecules. The COMPSRA pipeline (COMprehensive Platform for Small RNA Analysis) was applied to extract RNAs. Several miRNAs, piRNAs, snRNAs, snoRNAs, circRNAs and tRNAs were detected in the samples. Maximum number of circRNAs was detected followed by piRNAs and miRNAs in the muscle samples of sheep. This study is a step towards recognizing the non-coding RNAs in skeletal muscles of Indian sheep. Further, studies in the identification and delineation of biological roles of non-coding RNAs are required to improve understanding of complex biological processes of muscle development.

Keywords

Data mining, Muscle, NcRNA, RNA sequencing, Sheep