Microbial diversity and sensitivity profile of clinical skin wounds

A study was aimed to record the pattern of antimicrobial sensitivity and resistance against the commonly used antimicrobials. Samples were collected from the clinical cases of wound presented to the Referral Veterinary Polyclinic-Indian Veterinary Research Institute Izatnagar, (Uttar Pradesh). A total of 20 wound swab samples were collected and subjected to culture, isolation, identification and antibiogram assay to establish the pattern of antimicrobial resistance. It was observed that Staphylococcus spp. (42.5%) was the most predominant isolate followed by Streptococcus spp. (20%), Escherichia coli (15%), Bacillus spp. (15%) and Klebsiella spp. (7.5%). Staphylococcus spp. showed maximum sensitivity to co-trimoxazole (52.94%) and almost resistant to cefixime (88.24%). Streptococcus spp. showed highest resistance to cefixime (87.5%) and most sensitive to amoxyclav (62.5%). Escherichia coli isolates showed complete resistance to the clindamycin and cefixime (100%). Bacillus spp. were most sensitive to tetracycline and cotrimoxazole (83.33%) and Klebsiella spp. isolates showed complete resistance to clindamycin (100%). Majority of the pathogens were resistant to the cefixime and clindamycin. It will serve as guidelines to clinicians for appropriate use of antibiotic for wound treatment.