Histopathological Alterations in the Kidney of Cyprinus carpio After Exposure to Dimethoate (EC 30%)

This study was conducted to assess the histopathological damage of kidney in common carp, Cyprinus carpio after sub lethal exposure to dimethoate. In a short term (96 hr) study healthy juveniles of common carp were exposed to 0.96 mgl⁻¹ of dimethoate (60% of 96 hr LC₅₀), and a parallel control was run simultaneously. Kidney of exposed individuals exhibited remarkable changes in their histology in comparison to control. Prominent changes include shrinkage of glomerulus, and dilation of tubular lumen. Vacuolization, desquamation, hydropic swelling and hyaline degeneration of tubular epithelium is also observed. Cyst formation and hemorrhage also appear in certain specimens. Duration of exposure appears to have profound effect on kidney as with increasing duration of exposure histopathological damages become more severe.