Antibacterial activities of some antibiotics against clinical isolates of certain bacterial strains with special reference to Lantana camara leaf extracts

Fifteen clinical isolates comprising of Corynebacterium acnei (03), Escherichia coli (04), Klebsiella pneumoniae (03) and Staphylococcus aureus (05) were collected from Gandhi Medical College, Bhopal, India and their resistant pattern against four well known antibiotics; ciprofloxacin (CIP), erythromycin (E), gentamicin (GEN) and methicillin (MET) (all 10 μg disc⁻¹) were studied using disc diffusion method with Lantana camara leaves extract. Staphylococcus aureus (80% against MET and 60% against GEN) and Escherichia coli (75% against MET and 50% against E), in case of Klebsiella pneumoniae (66.67% against MET, GEN and CIP) and Corynebacterium acnei (66.67% against MET) species were found to be more resistant against the studied antibiotics as compared to the extracts of Lantana camara. No resistance was observed of Lantana camara leaves derived antibiotics against all the test isolates. It is concluded from these figures that microbial resistance against these antibiotics are increasing in our population which is alarming and therefore it is recommended to physicians to prescribe these antibiotics unless no other substitute is available in clinical practices.