Evaluationof demographic and clinical factors affecting disease outcome after acuteischemic stroke in patients admitted to a tertiary care centre in India

In the present study, we assessed the demographic and clinical factors that affect mortality and functional outcome in acute ischemic stroke (AIS) patients at the time of hospital discharge and at 18 months after discharge. The study was carried out in a total of 104 AIS patients admitted to Central India Institute of Medical Sciences (CIIMS), Nagpur, a tertiary care centre in Central India. Relationships between nominal variables in the demographic and baseline clinical characteristics among AIS patients in the categories of hospital outcome and long-term outcome were analyzed. Ischemic heart disease (IHD) and hypertension were found to be an associated risk factor for hospital death or dependency and clinical outcomes at 18 months after discharge in AIS patients respectively. 85% of older AIS patients (>50 years) who had an improved outcome at hospital discharge were found to have dependent/expired outcome at 18-months follow-up whereas 75% of younger AIS patients (< 50 years) who were discharged with dependent hospital outcomes were found to have improved outcome at 18 months follow-up. The result demonstrates a significant association of variables such as IHD, age, and HTN with the functional outcome at discharge time and at 18 months follow-up in AIS patients.