Usefulness of neo adjuvant chemo-Radiotherapy in colorectal carcinoma to improve the rate of surgeries

To improve the rates of surgeries feasible following neoadjuvant therapy Results: Total numbers of cases were twenty among them 14 were male & 6 were female. Out of 20 cases, 4(20%) were well differentiate adenocarcinoma, 8(40%) moderately differentiated adenocarcinoma, 5(25%) poorly differentiated adenocarcinoma, 2(10%) infiltrating type of adenocarcinoma and 1 (5%) mucinous adenocarcinoma. 20% of the patients underwent Low Anterior Resection, 35% of patients underwent Anterior Resection, 35% of the patients underwent Abdomino-Perineal Resection, 10% had undergone Loop Colostomy. Total number of patients who underwent APR was 35% which without the Neo-Adjuvant therapy would have been 60% i.e., 25% patients were benefited from a sphincter saving procedure. Neoadjuvant therapy may be considered a rational approach for treatment of curative rectal cancer. Volumetric reduction of neoplasia, mesorectum and lateral pelvic nodes was evident in 90% of the patients.