Study of insulin resistance in subclinical hypothyroidism patients

To study the levels of fasting plasma glucose, fasting serum insulin values and presence of insulin resistance (HOMA) in subclinical hypothyroidism patients compared to healthy controls. There was significant increase in fasting serum insulin (p=< 0.001), HOMA 1 (p=< 0.001) and HOMA 2 (p=< 0.001) values between subclinical hypothyroidism patients and controls. This study suggests that subclinical hypothyroid patients have significant alterations in carbohydrate metabolism. Insulin resistance which is known risk factor for development of diabetes and cardiovascular consequences is observed in subclinical hypothyroid patients too.