Esophageal dysplasia in high risk group and significance of agnor in esophageal dysplasia

Study of prevalence of various grades of dysplasia in the middle third of esophagus in asymptomatic individuals with high risk factors. AgNOR staining as a proliferation marker and prognostic indicator. The odds ratio for various risk factors were calculated. There was increase in AgNOR count with increasing dysplasia. Alcohol and smoking either alone or in combination with a duration of more than 10 years is likely to predispose an individual to dysplasia. Dysplasia is more prevalent in high risk group. AgNOR study simple, inexpensive and reliable proliferation marker.