Study of efficacy and safety of topical cyclosporine in vernal keratoconjunctivitis

The purpose of this study was to evaluate the efficacy and adverse effects of topical cyclosporine 0.05% in patients suffering from vernal keratoconjunctivitis(VKC). Atotal of 100 patients of VKC were treated with topical cyclosporine 0.05% eye drops. Symptoms and signs were observed while starting the treatment and at 4, 8 and 12 weeks of follow up. Scores for symptoms and signs and any ocular side effect were evaluated. There was significant reduction in symptom and sign scores of VKC with treatment by cyclosporine eye drop. No significant side effects were reported. Topical cyclosporine 0.05% is an effective and safe alternative treatment of VKC which helps to reduce the need for corticosteroids.