Synthesis of phenyl-1, 3-Thiazole substituted amino S-Triazines and studying their biological activity

Amino S-triazines exert antibacterial effects by non specific mechanism. A series of amino substituted S-triazines were synthesised and subsequently screened for their in vitro antibacterial activity against gram positive (Bacillus anthracis, Clostridium tetani, Staphyloccocus epidermis) and gram negative (Acetobacter aceti, Vibrio cholera, Escherichia coli) by broth dilution technique w. r. t. streptomycin. Compound and its derivatives showed good antibacterial activity.