Clinico-pathological changes in canine demodicosis with particular reference to dectomax therapy

Demodicosed canine exhibited presence of Demodex mites in skin scrapings examination; alopecia, erythema, rough body coat, hyperkeratinisation; a reduction in Hb and TEC levels together with an increase in TLC, lymphocytes, eosinophils, serum bilirubin, serum ALT, serum AS T and bromosulfophthalein retention time. Histopathology revealed lesions in skin. The study of immune response revealed significantly (P<0.05) reduced total immunoglobulins with suppression of cell mediated immunity. Following therapy with Dectomax, the clinical, haematological, histopathological and immune system responses were redirected towards normalcy alongwith drastically minimised cutaneous histopathological changes as compared with those of the infected animals.